In contrast, recent evidence suggests that the decreased abundance of Clostridium_sensu_stricto_1 in intrauterine growth restricted (IUGR) piglets is negatively correlated with plasma proinflammatory cytokine (IL-1β, TNF-α, and IFN-γ) levels (Huang S. et al., 2019). This evidence concerns the gene IFNG and fetal growth restriction.