Sixteen pathways (e.g., the proteasome, PPAR signaling, cancer, zeatin biosynthesis, protein processing in endoplasmic reticulum, cellular antigens, other glycan degradation, secondary bile acid biosynthesis, electron transfer carriers, renal cell carcinoma, and adipocytokine signaling pathways) were significantly more abundant in the C group. The gene discussed is PPARA; the disease is renal cell carcinoma.