CHD in patients with hyperLp(a) and LMW apo(a) phenotype (Group 4) was manifested by 5 years earlier than in patients with HMW apo(a) type (Group 1): median [95% CI] 45 [45;47] vs. 50 [48;50] years (p < 0.01). This evidence concerns the gene AOPEP and coronary artery disorder.