Herein, compared to the LPD group, the HPD group up-regulated mRNA levels of the ampkα1, ampkα2, ampkβ1, ampkβ2, ampkγ1 and ampkγ2, and increased the AMPKα1 phosphorylation level. This evidence concerns the gene PRKAA1 and disseminated peritoneal leiomyomatosis.