Compared to the LPD group, HPD group up-regulated the mRNA levels of beclin1, atg1a, atg1b, atg101, atg13, atg3, atg4b, atg4d, atg5, atg7, atg8a and atg8b (P ≤ 0.05) (Figure 2B), increased the protein levels of LC3B-II and the phosphorylation level of Beclin1 (P ≤ 0.05) (Figures 2C,D), and up-regulated the mRNA expression of many fatty acid β-oxidation genes (acads, acadm, acadvl, acadsb, acox1, acox3, hadh and hadhb) (P ≤ 0.05) (Figure 2E), and increased NEFA content (P ≤ 0.05) (Figure 2F). Here, ATG4D is linked to disseminated peritoneal leiomyomatosis.