ARNT and lung cancer: Later on, it was found that Dp (10–40 μM) did not affect the growth and proliferation of lung cancer cell line (A549 or NCI-H460) but averted the CoCl2 (200 μM)- and EGF (20 ng/ml)-provoked expression of hypoxia-inducible factor-1α (HIF-1α) protein without altering the expression of HIF-1β in lung cancer, breast cancer (MCF-7), and prostate cancer (PC3M) cell lines.