The relatively high levels of inflammatory cytokines, such as IL-6, in patients undergoing hemodialysis (median, 7.1 pg/mL; range, 2.2–163.5 pg/mL) (52), those with lung cancer (mean, 30.3 ± 40.2 pg/mL) (15), and those with Crohn disease (mean, 13.8 ± 13.4 pg/mL) (53), show a positive correlation with REE. The gene discussed is IL6; the disease is Crohn disease.