We identified that 24 significant features, including BMI, TNM stage, T stage, N stage, tumor size, chemotherapy, LDH/PA, LDH/ALB, GGT/PA, GGT/ALB, ALP/PA, ALP/ALB, PLT/PA, PLT/ALB, LYM/PA, NEU/PA, NEU/ALB, ALB/CREA, PA/CREA, MON/PA, MON/ALB, PNI, GRIm score, and CONUT score, were all well correlated with the OS in CRC patients (Table S2). This evidence concerns the gene ALB and neoplasm.