RUNX3 and non-small cell lung carcinoma: In light of both local relapse and distant metastasis contributing to worse outcome in the postoperative setting and the epigenetic regulation that histone modification might have on oncogenes and TSGs, we thus hypothesized that assessment of H3K27me3/RUNX3 co-expression might probably play some role in predicting the surgical outcome of NSCLC patients after radical resection.