The results were as follows: MSH2 gene expression levels in KIRC, LUSC, STAD, and UCEC were positively correlated with MSI, while lymphoid neoplasm diffuse large B cell lymphoma (DLBC), PRAD, and THCA showed a negative correlation between MSH2 gene expression levels and MSI. The gene discussed is MSH2; the disease is diffuse large B-cell lymphoma.