A high-amplification frequency of TEN1 was observed in breast invasive cancer (BRCA), liver hepatocellular carcinoma (LIHC), mesothelioma (MESO), and uterine carcinosarcoma (UCS), while a relatively high deletion rate of CTC1 and STN1 was found in colon adenocarcinoma (COAD), lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), and LIHC and prostate adenocarcinoma (PRAD) (Figure 1C). The gene discussed is CTC1; the disease is colon adenocarcinoma.