Three bioinformatics studies based on the clinical gastric cancer samples retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases indicated that GGT5 was included in prognostic gene signatures, and overexpression of GGT5 was inversely correlated with the survival in GC patients (Wei et al., 2020; Wen et al., 2020; Ye et al., 2021). The gene discussed is GGT5; the disease is gastric cancer.