GSEA indicated that signaling by interleukins, the VEGFA-VEGF2 signaling pathway, pathways in cancers, the PI3K/Akt signaling pathway, the anti-inflammatory response favoring Leishmania, and immunoregulatory interactions between lymphoid and nonlymphoid cells were closely correlated with the GGT5-high phenotype. This evidence concerns the gene GGT5 and cancer.