Moreover, evidence from clinical practice suggests that PD patients carrying mutations of the GBA gene (GBA-PD) may present more frequently dysautonomic manifestations and REM sleep behavior disorder (RBD) than patients with idiopathic Parkinson’s Disease (iPD; Brockmann et al., 2011; Gan-Or et al., 2016; Petrucci et al., 2020). Here, GBA1 is linked to Parkinson disease.