Interestingly, the E3 ubiquitin ligase Parkin, an enzyme that is also involved in mitophagy and has been implicated in early onset Parkinsonism (Kitada et al., 1998; Dikic and Elazar, 2018), seems to antagonize Bassoon in this function (Montenegro-Venegas et al., 2020). Here, PRKN is linked to Parkinsonism.