When circRPAP2 binds to SRSF1, SRSF1 does not appear to bind to PTK2 pre-mRNA, interfering with the alternative splicing effect of SRSF1 on PTK2 and leading to the reduction in PTK2 mRNA and protein expression, ultimately inhibiting the proliferation and migration of BC. This evidence concerns the gene SRSF1 and breast cancer.