TNF and type 1 diabetes mellitus: The -308 G/A polymorphism of TNF-α was also correlated with T2DM and T1D susceptibility among Iranian and Saudi cases, respectively [48, 49]. Regarding a previous study on Egyptian cases, the level of TNF-α was positively associated with total cholesterol, LDL-C, FBG, HbA1c, and creatinine in patients with diabetic foot.