HGF and neoplasm: In comparison to TCh3, TAb2 tumor lines overexpressed the components in differentiation of monocytes and EMT/tumor progression pathways (Fig. 3C, D), for example, TAb2 tumor cells expressed an increased level of CSF1 (Fig. 3C), HGF, and CXC chemokine ligand 12 (CXCL12) (Fig. 3D) which activates downstream pathways correlated with metastasis and survival/proliferation of tumor cells [46–49].