ACE and diabetes mellitus: In terms of concomitant cardiac medications, the two arms were well balanced (statins [95% of participants], angiotensin converting enzyme inhibitors, angiotensin II receptor blockers, anti-platelet, anti-coagulation, diabetes medications, calcium channel blockers, diuretics, anti-anginal, and nonsteroidal anti-inflammatory drugs—NSAIDs), though the placebo arm had more participants on beta-blockers (49% vs 33%) and fewer participants on alpha-blockers (7% vs 12%).