C1QBP and leukoencephalopathy with calcifications and cysts: Similarly, in vitro rescue experiments also revealed that C1QBP knockdown reversed the circMTCL1 enhancing effect on LSCC biological characteristics including proliferation ability, invasion and migration ability in both TU212 and LCC cells determined by EdU (Fig. 3h and Fig. S4f), transwell (Fig. 3i and Fig. S4g) and wound healing assays (Fig. 3j and Fig. S4h).