We analyzed the influence of the ATX-LPA axis on functional properties and IL-8, IL-6 and TNF-alpha secretion of different breast cancer cell lines categorized into five subtypes according to Dai et al.29: luminal A (MCF-7), luminal B (BT-474), HER2-positive (SKBR-3), triple-negative A (MDA-MB-468), and triple-negative B (MDA-MB-231). The gene discussed is TNF; the disease is breast carcinoma.