CRY1 and Anxiety: Average anxiety scores for individuals with PER3B-AG and CRY1-CG genotypes were higher (males: 54.8 ± 4.1; females: 46.7 ± 2.5) than for individuals of other genotypes (males: 41.3 ± 0.8, females: 44.8 ± 0.6; Fig. 2A,B).