ATG7 and Hyperglycemia: Human umbilical vein endothelial cells (HUVECs) were exposed to conditioned media from ad-ATG7-transduced CSCs in hyperglycemia, and they were able to form significantly more closed loops (Fig. 7B, C) with a significantly higher total tube length (Fig. B, D), as compared to ad-LacZ-transduced CSCs.