In addition, the expression of many sensory nerve markers, including Tac1 and TRPV1, and the lung fiber innervation patterns themselves are plastic and can be modulated by inflammation and infection (Hoyle et al., 1998; Hunter et al., 2000; Carr and Undem, 2001; Zhang et al., 2008; Lieu et al., 2012). The gene discussed is TAC1; the disease is infection.