MKI67 and neoplasm: In addition, we performed IHC staining for Ki-67 and SF3A3 proteins in xenograft tumor tissue sections and found that the level of circSCAP was significantly inversely correlated to Ki-67 and SF3A3 (Fig. 7E and F), but the level of SF3A3 was positively associated with Ki-67 (Fig. 7E and F).