SPICE1 and lung carcinoma: Most of the examined centriolar/centrosomal genes showed no difference or even a slight down-regulation between lung cancers and paired non-malignant tissues; however, the expression levels of STIL, SASS6, SPICE1, PLK4, CEP295, POC5, and CEP152 displayed significantly high T/N ratios in lung cancer patients (Table 1).