First, univariate logistic regression was used to screen CAD-related DEARGs, Fig. 5A showed there were 23 genes (ABHD5, ACSL1, ALPL, AMBRA1, ARHGAP26, CASP4, CEBPB, CFLAR, DDIT4, DENND3, FADD, FOS, GABARAPL1, GLIPR2, GPR18, LAMP2, LRRK2, MAPK14, MTMR3, NAMPT, NLRX1, NOD2, NRBF2, RALB, S100A8, TBC1D14, WDFY3) selected from 27 DEARGs. Here, NOD2 is linked to coronary artery disorder.