Astrocytes, presumably the main target cell of an anti-GFAP autoimmune reaction, play a vital role in multiple processes in the brain, including synapse formation, clearance of neurotransmitters, or modulation of synaptic activity and plasticity (reviewed in Vasile et al 2017), and an anti-GFAP autoimmunity, as reported in our manuscript, might therefore very well be linked to several neurological disorders as well to the specific autoimmune GFAP astrocytopathy (Kunchok et al 2019). Here, GFAP is linked to nervous system disorder.