Its mechanism is to inhibit P-gp and down-regulate nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) and phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) pathways, inducing apoptosis by suppressing the growth of cancer cells (Kim et al., 2021). The gene discussed is AKT1; the disease is cancer.