In terms of the pattern of tumor uptake, PSMA-PET/CT revealed diffuse infiltration, bilateral focal and unilateral focal prostate tumor in 64% (37/58), 17% (10/58) and 19% (11/58) of PSMA-PET/CTpost patients, respectively, and in 64% (37/58), 15% (9/58) and 21% (12/58) of PSMA-PET/CTpre patients in comparison (Supplemental Fig. 1). This evidence concerns the gene FOLH1 and neoplasm.