CHCHD10 and neurodegenerative disease: CHCHD10 is implicated in neurodegenerative diseases as inducing aggregation of TDP-43 (McCann et al. 2020), a pathological feature of several neurodegenerative diseases (Woo et al. 2017; Neumann et al. 2007) Moreover, amyloid-like myo-granules were formed by TDP-43 and RNA in regenerating muscle (Vogler et al. 2018).