As shown in Figure 1F, high levels of both CD68+ and CD68+CA12+ cell infiltration in tumor regions indicated worse patient survival, with the CD68+CA12+ groups exhibiting better prognostic values than the CD68+ groups (CD68+: P = 0.012 for overall survival [OS], P = 0.0368 for tumor recurrence [TR]; CD68+CA12+: P = 0.0052 for OS, P = 0.0037 for TR). This evidence concerns the gene CD68 and neoplasm.