CD14 and hepatocellular carcinoma: Moreover, in addition to supernatants from HepG2 cells, TSN from other hepatoma cell lines (SK-Hep-1, Hep3B, and PLC/PRF/5), but not supernatants from the normal liver cell line HL-7702, could also induce the upregulation of CA12 in CD14+ cells (Figure 2I).