Consistently, in situ immunofluorescence staining of human HCC samples showed that, while peritumoral monocytes exhibited enhanced GLUT1 expression compared with those from nontumor or intratumoral areas, both peritumoral and intratumoral infiltrating monocytes and macrophages showed significantly upregulated expression of CA12 compared with those from paired nontumor tissues. The gene discussed is SLC2A1; the disease is hepatocellular carcinoma.