Since it has been reported that myriad cytokines were raised in the blood of COVID‐19 patients (Mangalmurti & Hunter, 2020), we examined the ones that could potentially affect permeability, including IL‐1α, IL‐1β, TNF‐α, IFN‐γ, and VEGF, in the cases with or without GI symptoms. This evidence concerns the gene IL1B and COVID-19.