Giacomelli and colleagues conducted their screen in isogenic TP53+/+ and TP53−/− human A549 lung adenocarcinoma cells while Boettcher et al. did the same in a K562-TP53wild type CML cell line which expressed a GFP reporter at the CDKN1A locus [33, 45]. This evidence concerns the gene TP53 and lung adenocarcinoma.