Studies have shown that DNAm profiles at subsets of CpGs overlap between individuals with BAFopathies carrying variants in SMARCA2 that cause NCBRS, and in ARID1B, SMARCB1, and SMARCA4 that lead to Coffin-Siris syndromes type 1, 3, and 4, respectively. The gene discussed is ARID1B; the disease is intellectual disability-sparse hair-brachydactyly syndrome.