Furthermore, we assessed m6A modifications in previously glioma associated lncRNAs: LINC00461, HOTTIP, CRNDE, TUG1, XIST, MALAT1 and NEAT1. To our knowledge we are first to report m6A modifications in LINC00461, HOTTIP, and CRNDE lncRNAs in GSCs. Here, HOTTIP is linked to central nervous system cancer.