Furthermore, we assessed m6A modifications in previously glioma associated lncRNAs: LINC00461, HOTTIP, CRNDE, TUG1, XIST, MALAT1 and NEAT1. To our knowledge we are first to report m6A modifications in LINC00461, HOTTIP, and CRNDE lncRNAs in GSCs. This evidence concerns the gene MALAT1 and central nervous system cancer.