Lastly, KRT1high BLCA patients had significantly higher expression of EGFR and MKI67, suggesting that proliferation is potentiated in this group; this complements the survival analysis (high KRT1 is unfavorable in BLCA) and IHC data (KRT1 staining is higher in cancer than normal specimens). The gene discussed is EGFR; the disease is bladder transitional cell carcinoma.