To assess the role of CXCR3 expression on IFN-γ+ Vγ4 in vivo, IFN-γ+ γδ T cells from WT and CXCR3-/- mice were transferred into TCRδ-/- mice respectively, and liver fibrosis was induced. The gene discussed is CXCR3; the disease is Hepatic fibrosis.