The most commonly studied markers are neutrophil gelatinase-associated lipocalin (NGAL), interleukin-18 (IL-18), kidney injury molecule-1 (KIM-1), L-type fatty acid-binding proteins (L-FABP), and cystatin C [1, 9, 10], all of which are associated with improved early kidney injury detection, compared with traditional tests based on creatinine and GFR. The gene discussed is HAVCR1; the disease is kidney injury.