In addition, 65% (15/23) of the CRC patients with distant metastasis had a NAT miR-509-3p expression greater than the global median, while only 45% (36/80) patients from the non-metastatic group showed a median-high expression of the miRNA within the NAT tissues (p = 0.0131) (Fig. 6C). This evidence concerns the gene BRD2 and colorectal carcinoma.