IDH3A and retinal degeneration: It was shown that human IDH3A and IDH3B mutations are associated with severe early childhood-onset retinitis pigmentosa, and mouse Idh3a mutations lead to retinal degeneration (Hartong et al., 2008; Fattal-Valevski et al., 2017; Pierrache et al., 2017; Findlay et al., 2018; Tommasini-Ghelfi et al., 2019).