Also, multivariate Cox analysis further narrowed these candidates into 10 genes, including AC108479.3, FAM207A, GS1-304P7.1, LINC00540, LYPD3, NDST3, RP11-379P1.4, RP11-615I2.1, RP11-672L10.6, and TREML2, which were significantly correlated with OS in AML; AC108479.3, NDST3, RP11-379P1.4, and RP11-672L10.6 benefited AML, while FAM207A, GS1-304P7.1, LINC00540, LYPD3, RP11-615I2.1, and TREML2 had a poor impact on AML (Supplementary Table S1). The gene discussed is LYPD3; the disease is acute myeloid leukemia.