Furthermore, multiple other SNPs exhibited significant associations with severe COVID-19, including rs77534576 (TAC4), rs111837807 (CCHCR1), rs766826 (ELF5), rs10774679 (OAS1/OAS3/OAS2), rs12809318 (FBRSL1), rs61667602 (CRHR1), rs2109069 (DPP9), rs11085727 (TYK2), rs1405655 (NR1H2), and rs13050728 (IFNAR2). This evidence concerns the gene TYK2 and COVID-19.