ESR2 and colorectal carcinoma: In a recent publication for the validation of ERβ antibodies in 44 different tissues, 14C8 antibody showed in CRC IHC the same intensity band as PPZ0506, which was reported to be the most specific anti- ERβ antibody, and that correlated with ERβ mRNA levels detected in the CRC tissue [Figure 3, see reference (48)].