With respect to psychological distress, studies have investigated associations between inflammatory markers and psychological distress in adults, and reported cross-sectional associations with C-reactive protein (CRP), in large population studies (Wium-Andersen et al., 2013; Baek et al., 2019), and prospective associations with Interleukin 6 (IL-6; Virtanen et al., 2015). The gene discussed is IL6; the disease is Abnormal emotional state.