In addition, Eymael et al. (2018) observed that CD44 deficiency results in decreased glomerular cell proliferation and reduced albuminuria, which revealed that acquired glomerular CD44 expression by activated PECs is required for the pathogenesis of crescentic glomerulonephritis and collapsing FSGS (Eymael et al., 2018). This evidence concerns the gene CD44 and crescentic glomerulonephritis.