The Th1 gene expression is responsible for the production of IFN- γ, which induces the activation of a set of chemokines, including CXCL10, that in vitiligo patients is responsible for the chemotaxis of CD8+ T cells to melanocytes and to start the process of destruction of these cells (Rashighi et al., 2014). This evidence concerns the gene CD8A and vitiligo.