PC1 was mostly determined by biomarkers of COVID-19 severity, neutrophils to lymphocytes ratio (DH6), lactic dehydrogenase (M25), C-reactive protein (M13) and pulmonary involvement (CT23), and health biomarkers albumin (M24) oxygen saturation (O2) and arterial oxygen pressure to inspired fraction of oxygen ratio (O3). The gene discussed is ALB; the disease is COVID-19.