MAPT and Alzheimer disease: Aβ oligomerization has also been subject for study as a potential candidate biomarker for diagnosis of AD (An et al., 2017; Meng et al., 2019; Youn et al., 2020), and it has been reported to be correlated with CSF Aβ42, Pittsburgh compound B (PiB) PET (PiB-PET), CSF phosphorylated tau, and CSF total tau (Wang et al., 2017).