VAMP2 mRNA expression was significantly different when AD (n: 73; 0.63: 0.50–0.73), MD (n: 122; 0.71: 0.55–0.95), MCI (n: 103; 0.75: 0.56–0.94) and CT (n: 140; 0.63: 0.47–0.81) individuals were compared (p < 0.001) (Figure 2A). This evidence concerns the gene VAMP2 and Alzheimer disease.