Considering MCI subjects with known clinical evolution, at recruitment, when all these individuals had a diagnosis of MCI, VAMP2 expression was significantly augmented in MCI that converted to MD (n: 18) compared to those converted to AD (n: 19) (0.87: 0.74–1.00 vs. 0.67: 0.42–0.74, p = 0.001) (Figure 2B). Here, VAMP2 is linked to Alzheimer disease.