In addition, the inhibition of MEK/ERK 1/2 signaling by IP-Se-06 resulted in antiproliferative activity, as well as in the inhibition of p38 mitogen-activated protein kinase, thereby leading to inhibition of inflammasome complex proteins, such as NLRP3 and caspase-1 in glioblastoma cells. This evidence concerns the gene NLRP3 and glioblastoma.