Recurrent extreme hyperferritinemia was noted 1 week prior to her death (and 99 days following the first ferritin peak) concurrent with the onset of MODS and an increased IL-6 (510.9 pg/mL; she was treated with tocilizumab on HD 176, and IL-6 on HD 178 was 1,423 pg/mL). Here, IL6 is linked to isolated hyperferritinemia.