Additionally, since parvalbumin basket cells and molecular layer interneurons express GABAAR δ subunits (Glykys et al., 2007; Yu et al., 2013), it is possible that changes in interneuronal tonic GABA currents could influence their excitability and alter GC sIPSC frequency as observed in epilepsy (Yu et al., 2013). The gene discussed is PVALB; the disease is epilepsy.